Research Articles
Plasticizers and the Glass Transition Temperature: Mechanisms, Measurement, and Applications in Amorphous Pharmaceutical Solids
This article provides a comprehensive review of the effect of plasticizers on the glass transition temperature (Tg) in amorphous solids, with a focus on pharmaceutical applications.
Beyond Functionality: Economic vs. Technical Methods for Polymer Quality in Drug Development
This article provides a comprehensive analysis of economic and technical substitutability methods for assessing polymer quality in pharmaceutical applications.
Glass Transition vs. Melting Temperature: A Definitive Guide for Pharmaceutical Scientists & Material Researchers
This article provides a comprehensive and current analysis of the critical distinction between glass transition temperature (Tg) and melting temperature (Tm) for researchers and drug development professionals.
The Ultimate Guide to Determining Critical Formulation Temperature for Lyophilization: Methods, Protocols, and Optimization Strategies
This comprehensive guide for researchers, scientists, and drug development professionals explores the critical formulation temperature (Tc, Tg', Teu) in lyophilization.
Mastering Polymer Processing: A Design of Experiments (DoE) Guide for Pharmaceutical Researchers
This comprehensive guide details the application of Design of Experiments (DoE) methodology to systematically optimize critical polymer processing parameters for drug delivery systems and biomedical devices.
Degradation by Design: Programming Biopolymers for Controlled Breakdown in Biomedical Applications
This article provides a comprehensive overview of the 'degradation by design' paradigm for biopolymers, targeting researchers, scientists, and drug development professionals.
Mastering the Deborah Number: A Key to Predicting Polymer Behavior in Drug Delivery and Biomedical Applications
This article provides a comprehensive exploration of the Deborah number (De), a fundamental dimensionless quantity in rheology crucial for understanding polymer processing dynamics.
Glass Transition Temperature (Tg) Analysis: DSC vs DMA - A Comprehensive Guide for Pharmaceutical Scientists
This article provides a detailed comparative analysis of Differential Scanning Calorimetry (DSC) and Dynamic Mechanical Analysis (DMA) for measuring the glass transition temperature (Tg) of amorphous solid dispersions, polymers, and...
Mastering Tg Measurement in Polymers: A Comprehensive DSC Protocol Guide for Drug Development Researchers
This definitive guide provides drug development scientists and researchers with a complete framework for measuring the glass transition temperature (Tg) of polymers using Differential Scanning Calorimetry (DSC).
Mastering DSC for Polymer Crystallinity: A Complete Guide for Pharmaceutical and Material Scientists
This comprehensive guide explores Differential Scanning Calorimetry (DSC) as a critical tool for quantifying polymer crystallinity, essential for drug delivery system development and material science.