Research Articles
Modeling Uncertainty: How B-Spline Approximation Enhances Molecular Weight Distribution Control in Drug Development
This article provides a comprehensive overview of B-spline approximation models for controlling Molecular Weight Distribution (MWD) in polymer-based therapeutics and drug delivery systems.
Avrami vs. Gompertz Models: A Practical Guide for Modeling Crystallization Kinetics in Drug Development
This article provides a comprehensive comparison and practical guide to the Avrami (Johnson-Mehl-Avrami-Kolmogorov) and Gompertz models for analyzing crystallization kinetics, a critical process in pharmaceutical development.
Accelerating Drug Discovery: How Automated Forcefield Parameterization Predicts Glass Transition Temperature (Tg)
This article explores the transformative role of automated forcefield parameterization in predicting the glass transition temperature (Tg) of amorphous solid dispersions and polymeric excipients.
Optimizing Pharmaceutical Injection Molding with Artificial Neural Networks: A Guide for R&D Scientists
This article provides a comprehensive overview for researchers and drug development professionals on leveraging Artificial Neural Networks (ANNs) to optimize injection molding parameters for pharmaceutical manufacturing.
Mastering Accelerated Aging: A Complete Guide to the Arrhenius Equation for Polymer Stability in Pharmaceuticals
This article provides a comprehensive guide for researchers and drug development professionals on applying the Arrhenius relationship to predict polymer degradation and shelf life in pharmaceutical products.
Biopolymer Batch Consistency: Strategies to Control Variability for Reliable Biomedical Applications
This article addresses the critical challenge of biopolymer batch-to-batch variability, a major hurdle in reproducible research and drug development.
Understanding and Correcting Tg Prediction Outliers in Molecular Dynamics Simulations: A Guide for Computational Researchers
This article provides a comprehensive framework for researchers and computational scientists working in drug development to identify, understand, and resolve outliers in glass transition temperature (Tg) predictions from molecular dynamics...
ATRP vs RAFT Polymerization: A Comprehensive Guide to Dispersity Control for Biomedical Applications
This article provides a comprehensive, up-to-date comparison of Atom Transfer Radical Polymerization (ATRP) and Reversible Addition-Fragmentation Chain-Transfer (RAFT) polymerization, with a focused analysis on their capabilities for achieving low dispersity...
AI and Machine Learning in Supramolecular Biomaterials: Revolutionizing Design for Drug Delivery and Therapeutics
This article provides a comprehensive analysis of the transformative integration of artificial intelligence (AI) and machine learning (ML) with supramolecular chemistry for advanced material design.
AI-Powered Predictive Models for Polymer Aging: Accelerating Material Lifetime Assessment in Medical Devices and Drug Development
This article explores the transformative role of artificial intelligence (AI) and machine learning (ML) in predicting the aging behavior and service lifetime of polymers critical to biomedical applications.